Subcapsular intratesticular assay: a preliminary screening method for putative male antifertility drugs

A Method for Murine Islet Isolation and Subcapsular Kidney Transplantation

Since the early pioneering work of Ballinger and Reckard demonstrating that transplantation of islets of Langerhans into diabetic rodents could normalize their blood glucose levels, islet transplantation has been proposed to be a potential treatment for type 1 diabetes. More recently, advances in human islet transplantation have further strengthened this view. However, two major limitations pre...

Fluorometric method for phenylalanine microplate assay adapted for phenylketonuria screening.

We adapted the method of McCaman and Robins for fluorometry of phenylalanine to a microplate assay for routine phenylketonuria screening. Sensitivity is 15 mumol/L for the plasma assay and 30 mumol/L for the dried blood-spot assay, with CV less than 10% for both assays. Results for human plasma by microplate assay correlated well (r = 0.99) with results of amino acid analyzer determination of p...

Assay of cardiotonic drugs by a chick embryo method.

Antifertility, Abortifacient and Fertility Promoting Drugs from Dandakaranya

In this article, 26 folKlore claims on Antifertility, Abortifacient and Fertility - promoting drugs gathered from the tribals of Dandakaranya during the Medico-Ethno-Botanical explorations undertaken by the authors are presented. suggesting scientific screening of these claims for establishing their validity and acceptability so as to make use of them, with modifications if any, in the National...

A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection.

OBJECTIVES Plasmodium gametocytes, responsible for malaria parasite transmission from humans to mosquitoes, represent a crucial target for new antimalarial drugs to achieve malaria elimination/eradication. We developed a novel colorimetric screening method for anti-gametocyte compounds based on the parasite lactate dehydrogenase (pLDH) assay, already standardized for asexual stages, to measure ...